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Item Number: 3050

Saccharomyces Boulardii Powder 15g

£9.13 Exc. VAT

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P U R E  •  M I X   &   M A T C H  •  V E G A N

+ Pure Formula
Here at Epigenetics, the quality and purity of each ingredient is integral to our development of effective, bioavailable formulas. Our products are naturally pesticide-free and completely free from artificial fillers, additives, lubricants, binders, bulking agents and preservatives.

+ Designed for Mixing
Create your own bespoke probiotic mix without needing to take lots of capsules daily. Combine with other Epigenetics probiotic powders or take alone. Each sachet provides 15g (15 servings); combine to increase your supply whilst continuing to take 1g a day.

+ Vegan Friendly
We respect nature and as such we do our part and only use vegan-friendly ingredients in our Saccharomyces Boulardii.

+ Letterbox Friendly
Our powders come in small sachets, designed for easy, contact-free delivery. The smaller design leads to a reduced carbon footprint during the shipping process.

Please be aware that due to the nature of our probiotic products, we will not be able to receive this item back should you wish to return it. For this reason it’s advised that you take care when ordering, as we may not be able to offer you a refund.


Saccharomyces boulardii

Saccharomyces boulardii is a non-pathogenic yeast that occurs naturally in the human digestive system and has been extensively studied for its probiotic properties. It was first isolated from the skin of lychee and mangosteen fruits in 1923. Since then, Saccharomyces boulardii has been used as a probiotic that offers a range of beneficial effects, including enhancing gut barrier function, eliminating harmful pathogens, producing antimicrobial peptides, stimulating the immune system, and suppressing inflammation. Its therapeutic applications are primarily focused on preventing and treating various gastrointestinal tract disorders, such as diarrhoea symptoms (1).

Those with a weakened immune system, digestive tract issues or yeast allergies should consult their healthcare practitioner before using this product.

Epigenetics probiotic Saccharomyces boulardii is produced in a vegan friendly and convenient delayed release capsule. Recommended daily dose is 1 serving per day taken after a meal, or as directed by a healthcare practitioner. This product is not intended to be used as an alternative to a varied diet.

Add a pot & scoop to your order to better store your probiotics and make dosing and mixing powders easier.


Ingredient Amount per serving ECRDA* %DV*
Inulin (from Jerusalem artichoke) 675 mg
Saccharomyces boulardii 250 mg (5B CFU)

† Percent Daily Reference Intakes (RI) not established.

INGREDIENTS: Organic Jerusalem artichoke tuber extract (Helianthus tuberosus), Saccharomyces boulardii.

Suitable for vegans

Read More

Research suggests that Saccharomyces boulardii may help to treat certain infections. Helicobacter pylori is a type of bacteria commonly found in the digestive tract of individuals, which can sometimes lead to indigestion and stomach ulcers. A study conducted in 2019 analysed data from 18 previous trials to investigate the efficacy of using a combination of Saccharomyces boulardii and antibiotics in treating this infection. The study found that this combination was more effective than using antibiotics alone in eradicating the bacteria. Additionally, those who took Saccharomyces boulardii experienced fewer side effects, such as diarrhoea and constipation, and were less likely to discontinue treatment than those who only took antibiotics (2).

Likewise, Saccharomyces boulardii has been shown to assist in anti-inflammatory protection by preventing the secretion of interleukin 8 in the gut during an E. coli infestation. This can lead to a reduction in the severity and toxicity of the bacterial invasion. Research has indicated that the presence of Saccharomyces boulardii does not decrease the number of adherent bacteria produced by E. coli, but rather reduces the number of intracellular bacteria by approximately 50%.  Saccharomyces boulardii is therefore considered a valuable tool in combatting E. coli infections and reducing associated inflammation (3).

The addition of boulardii to the treatment of ulcerative colitis patients has found to be effective. In animal models of inflammatory bowel disease (IBD), the combination of Saccharomyces boulardii and doxycycline has been shown to induce remission and prevent relapses. Saccharomyces boulardii has also been found to reduce the infiltration of Th1 cells and inhibit proinflammatory cytokine production in mice with IBD, while suppressing colitis and decreasing tissue levels in rats. In mice with colitis, Saccharomyces boulardii has been shown to reduce inflammation and intestinal colonisation by Candida albicans. Furthermore, the addition of Saccharomyces boulardii to baseline therapy has been found to improve intestinal permeability and reduce the frequency of bowel movements in Crohn’s disease patients (4).

Moreover, a study conducted to evaluate the potential of Saccharomyces boulardii in managing urinary tract infections (UTI) in children. The study aimed to investigate the impact of Saccharomyces boulardii on faecal E. coli, a common cause of acute and recurrent urogenital infections. The study involved 24 children who were administered Saccharomyces boulardii once a day at a dose of 5 billion for 5 days. Following treatment, a significant reduction in E. coli and yeast colonies was observed in the stool sample, indicating that Saccharomyces boulardii may have a role in the management of UTI in children (5).

It is important for certain groups to exercise caution when taking Saccharomyces boulardii. Elderly individuals, people with digestive tract diseases and those with weakened immune systems should consult with their healthcare practitioner before taking Saccharomyces boulardii. Similarly, individuals with yeast allergies may be allergic to products containing Saccharomyces boulardii and should avoid using them to prevent allergic reactions (6).

Product Information

Packaging: 15 g

Recommended daily dose, 1 serving taken last thing at night on a empty stomach. Put the powder into a glass, add 100 ml of water and stir until dissolved.

Serving size: 1g     Servings per container: 15

Store in a refrigerator out of reach and sight of children. Once opened, consume within 6 months.



  1. Trang Tran, P.D. (2023) What is saccharomyces boulardii?, Verywell Health. Available at: (Accessed: March 10, 2023).
  2. Saccharomyces boulardii probiotics: Uses and benefits (2023) Medical News Today. MediLexicon International. Available at: (Accessed: March 10, 2023).
  3. Czerucka, D., Dahan, S., Mograbi, B., Rossi, B., & Rampal, P. (2000). Saccharomyces boulardii preserves the barrier function and modulates the signal transduction pathway induced in enteropathogenic Escherichia coli-infected T84 cells. Infection and immunity68(10), 5998–6004.
  4. Novkovic, B. (2022) Top 9 saccharomyces boulardii health benefits (S. boulardii), SelfDecode Supplements. Available at: (Accessed: March 13, 2023).
  5. Benefits of saccharomyces boulardii for diarrhoea, IBD, Leaky Gut & More (2023) Nutri Advanced. Available at: (Accessed: March 13, 2023).
  6. Saccharomyces boulardii: Overview, uses, side effects, precautions, interactions, dosing and reviews (2023) WebMD. WebMD. Available at: (Accessed: March 13, 2023).


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